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This compound was also analyzed for mu-opioid receptor action, and like conolidine, was observed to possess no action at the positioning. Employing the same paw injection examination, numerous alternate options with higher efficacy have been found that inhibited the First ache response, indicating opiate-like activity. Given the different mechanism

Researchers have recently discovered and succeeded in synthesizing conolidine, a normal compound that shows assure like a powerful analgesic agent with a more favorable safety profile. Although the correct system of action remains elusive, it really is presently postulated that conolidine can have quite a few biologic targets. Presently, conolidine